Maps were constructed by stimulating each grid locus with one stimulation train (six pulses with random inter-pulse intervals of between 3 and 5 seconds).
Additionally, discomfort during mapping is documented (Table 2).> -wrap-foot> tabletable provides information about stimulation parameters including resting motor threshold (RMT, % of stimulator output), mapping intensity (% of RMT), stimulation train frequency, number of pulses in a stimulation train, and pain scores (according to the visual analogue scale, VAS).
At stimulation frequencies >32 Hz the firing probability strongly decreased and the few APs triggered at the beginning of the stimulation train were followed by a prominent plateau depolarization.
Each stimulation train was 500 ms in duration, approximating the time scale of normal reaching and grasping movements and the time scale of the neuronal activity that normally accompanies movement.
The amplitude of a 30 Hz stimulation train administered at the TA motor point was varied sinusoidally, thus changing the number of the recruited motor units, and hence the tension at the tendon, in the same fashion.
This paper aims to address this problem by determining what reference force (i.e., using either peak force or force at the time of stimulation) and type of stimulation (train of pulses (burst), doublet, and twitch) is the best technique to use.
In vitro, whole cell, current clamp recordings from ChR2-expressing GAL neurons in POA slices indicated that 10 ms blue light pulses at stimulation frequencies ≤2 Hz evoked single action potentials and entrained VLPO neurons in a temporally precise manner with each light pulse evoking a full action potential (crossing 0 mV level) for the entire duration of a 60 s stimulation train (Fig. 2a, b).
We only varied stimulation amplitude and fixed frequency, pulse width, and duration of stimulation train.
