Thus we had control over localized stimulation and the ability to monitor spatiotemporal responses over the entire explant.
As the HsmtSSB becomes more positively charged without its termini, the electrostatic forces between Hspol γ and HsmtSSB likely increase at 20 mM KCl, increasing the stimulation and the ability of Hspol γ to displace the HsmtSSB variants more easily.
Moreover, STAT5−/− neutrophils displayed a respiratory oxidative burst, increased expression of surface markers following stimulation, and the ability to migrate, to produce high quantities of TNF-α, and to phagocytose and kill bacteria.
Approaches based on RNA extracted from tissues also do not allow for direct manipulation of hormonal stimulation, limiting the ability to more directly detect genes regulated by androgens, which might serve as predictors of response to therapies targeting androgenic stimulation or as novel targets for alternate drug therapy in this androgen driven disease process.
The PMA/ionomycin lead to maximal T-cell stimulation, testing the ability of individual cell subsets to produce cytokines.
When stimulation surpasses the ability of the synapse to recycle vesicles (as often observed in vitro), all vesicle pools are depleted and are only slowly regenerated.
Finally, these cells had the capacity to differentiate into plasma cells after stimulation and the ability to function as antigen-presenting cells.
In this study, we described the impact of conditioning or concurrent vibrotactile stimulation on the ability of a subject to discriminate the temporal order of two stimuli delivered at two different loci on the skin.
Finally, we tested whether A3ARs could be targeted to enhance the phagocytic capacity of neutrophils using pHrodo S. aureus-labelled bioparticles, finding that 2-Cl-IB-MECA stimulation enhanced the ability of neutrophils to phagocytose the bioparticles (Fig 5C).
Due to the slow isometric kinetics of the soleus muscle, contractions have a high degree of fusion during 50 Hz stimulation, impairing the ability to measure contraction and relaxation times.
