Exact(15)
Multiple possible mechanisms may contribute to the therapeutic effects of DBS [for review see Benabid et al. (2002), McIntyre et al. (2004a), Vitek (2002)], e.g., (1) Neuronal activity is blocked because stimulation changes the activation of voltage-gated currents in the vicinity of the stimulating electrode (depolarization blockade) (Beurrier et al. 2001).
The receptive field of a neuron in the visual system can be defined as the spatial area in which stimulation changes the firing pattern of the neuron.
Here we test whether mechanical stimulation changes the mechanical behavior of the tissue.
According to this kinetic discrimination model, the signaling cascades that lead to hypertrophy are activated when hormonal stimulation changes the kinetics or the amplitude of the Ca2+ transients that generate cardiac contraction [9].
Although a few show some change in the pattern of negative BOLD activity when visual stimulation changes, it is not clear to what extent these changes are precise [7], [8], [9].
When it is excited the stimulation changes
Similar(45)
The Big 5 personality traits are defined as follows by [Hogan and Hogan (2007)]: Openness vs. closedness to experience: The degree to which a person needs intellectual stimulation, change and variety.
All segments that contained a visual stimulation change (rotating cross), or a motor response were excluded from further analysis.
Overall, we recorded 100 TMS/hd-EEG sessions in 10 healthy volunteers and we systematically performed 92 pairwise comparisons at the single-subject level between the TMS-evoked potentials obtained either using different stimulation parameters, namely site, intensity, and angle of stimulation (change comparison - C), or keeping stimulation parameters constant over time (no-change comparison - NC).
The amplitude of the negative-going peak was smaller during stimulation (change = -148 μV, CI = [-244 -54]), whereas the amplitude of the positive-going peak was larger during stimulation (change = 43 μV, CI = [8.6 76.7]), similar to the asymmetric waveforms typically seen during sleep slow waves (Vyazovskiy et al., 2009).
While CD40L stimulation changed the expression of 1194 genes and IL21 stimulation affected 902 genes, only 283 and 129 genes were modulated by lipopolysaccharide or BAFF receptor stimulation, respectively.
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