PBMCs were also stimulated with PMA/ionomycin to observe the IFN- γ production and CD107a expression in NKT-like cells.
This problem has motivated the development of iterative procedures for model identification, such as those proposed by Feng and Rabitz [ 13], who, using a closed-loop strategy, attempted to estimate how to stimulate and how to observe a system for identification purposes.
These researchers sometimes study the emergence of early processes of mathematical thinking in laboratory settings, where children are stimulated by suitable displays (to observe the emergence of one-to-one correspondences, counting, measuring, and so on).
Berning et al. [ 25] used custom stimulated emission depletion microscopy to observe neurons and the movement of dendritic spines in the cerebral cortex of a living mouse [ 25].
The underlying idea is to help the system biologist on how to stimulate and observe the system for the purpose of model identification.
Bathing is communal, with birds stimulated to participate by observing others.
Interestingly, the phagocytic capacity measured for the stimulated microglia was observed to be inversely correlated to the IL-6 release levels induced by the different α-Syn variants ( Figure 3A ).
They found that total lung clearance of radioaerosol was enhanced with IPV therapy, but it was unclear how much IPV stimulated cough contributed to the observed benefit [ 23].
Importantly, this increase of Nrf-2 activity in stimulated tBHQ treated CF cells is comparable to levels observed in stimulated normal cells, indicating a fundamental correction of the defect.
16 If similar kinesthetic sensations to those induced by mirror therapy could be stimulated by observing another person's limbs moving, this suggests that pain could be relieved by a more targeted treatment regimen.
