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It was the right place at a stimulating time.
To verify whether IPCs could secrete insulin as a result of sensing physiological glucose concentrations as beta cells do, we first detected the quantity of insulin secretion in different glucose concentrations and under different stimulating time frames.
"This is a stimulating time for people wanting to work in the industry," says Stirling.
Hilary Penrose said: "Apart from getting soaked by a wave, we've had a very stimulating time.
The second world war was a marvellously stimulating time for her, opening up new areas of professional possibility.
GARCH model performed better in stimulating time series with long-term memory.
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To discriminate CD4+CD25low T cells and CD4+CD25high T cells during T cells activation, we defined these two subsets of CD4+ T cells with different CD25 expression based on the anti-CD3/anti-CD28 Abs co-stimulated time: (i) CD4+CD25low T cells, stimulated time is less than 12 h; (ii) CD4+CD25high T cells, stimulated time is more than 48 h.
By comparing their signal intensities, peptides from the different FGF-2 stimulated time points could be relatively quantified.
Phosphopeptides that showed at least a 2-fold increase (arbitrarily chosen as a substantial increase) in tyrosine phosphorylation at either of the stimulated time points (5 min or 15 min) were clustered into 5 different groups (Fig. 4 and Table S4).
k-means clustering of the TNF stimulated time course microarray gene expression data, followed by functional enrichment analysis identified three biologically informative clusters related to apoptosis, cellular proliferation and angiogenesis.
Finally, the SAPH stimulated time-dependent increases in aggrecan and type II collagen deposition, two important NP extracellular matrix components.
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