Sentence examples for stimulating expression of from inspiring English sources

Type I interferons (IFNs) are expressed by all nucleated cells in response to viral pathogens and modulate innate and adaptive immune responses by stimulating expression of subsets of interferon stimulated genes (ISGs).

Adrenergic stimulation and cold stress in rodents increase energy expenditure by stimulating expression of Ucp1 in the interscapular BAT depot during the recruitment of BAT in this depot [ 21] and by the appearance of brown adipocytes in white adipose tissue (WAT) [ 8, 22, 23].

The constitutively activated SDF-1/CXCR4 axis has been shown to play a crucial role in promoting tumor growth through paracrine and/or autocrine stimulation of tumor cells, promoting tumor invasion and metastasis by stimulating expression of MMPs, and trafficking tumor cells to target organs or tissues along ligand gradients.

In primary macrophages a subset of rocaglates 1) synergized with low concentrations of IFNγ in stimulating expression of a subset of IFN-inducible genes, including a key regulator of the IFNγ network, Irf1; 2) suppressed the expression of inducible nitric oxide synthase and type I IFN and 3) induced autophagy.

Import of UA into XOR deficient cancer cells may further promote proliferation and survival in part by stimulating expression of COX-2.

While fungal protein secretion pathways differ from those of bacteria, high concentrations of MgSO4 may also affect membrane organization in eukaryotes, facilitating protein secretion and/or stimulating expression of genes that contribute to enhanced protein production and secretion.

While Rb may be required solely for survival of muscle, bone, white fat and lymphoid cells, these studies suggest that it is actively engaged in sequestering inhibitors of differentiation or stimulating expression or activity of differentiation factors in stem/progenitors cells at the stage of bifurcation into different cell lineages.

Lipids A do not induce direct cytotoxicity on tumor cells but trigger the immune system [ 16, 19] stimulating expression and secretion of several cytokines [ 20, 21], and activating the inducible nitric oxide synthase (NOSII) [ 22].

In many cases these multiple genes did not appear to be the result of recent duplications, or to function only as a means of stimulating expression by increasing gene dosage, as the homologs were located in varying functional genetic contexts.

Buckle, A. M. & Hogg, N. The effect of IFN-gamma and colony-stimulating factors on the expression of neutrophil cell membrane receptors.

Expression of factors stimulating angiogenesis and lymphangiogenesis was not induced by ESWT and/or CPDT (Siems et al 2005).