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Taken together, our results suggest that CREB regulates AP-2α expression via two pathways: 1) by directly binding the AP-2α promoter and repressing its activity, and 2) by stimulating expression of E2F-1, which also binds to AP-2α promoter and represses its activity.
In this mechanism, TNF- α plays a key role in the degradation process by stimulating expression and release of proteases, such as collagenases, aggrecanases, and MMPs, which degrade collagen and aggrecan.
IL-1β and TNF-α play key roles in the destructive process by stimulating expression and release of proteases, such as collagenases and aggrecanases, including matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinase with trombospondin repeats (ADAMTS), which degrade collagen and aggrecan.
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Subsequently, RT-PCR results indicated that xylR overexpression stimulated expression of xylose assimilation genes synergistically with exposure to xylose.
Systemic inflammation stimulates expression of TLR and increases CSF cytokines and leukocytes levels, probably by affect blood-cerebrospinal fluid barrier (BCSFB) regulation [150].
As a consequence, the ability of β subunits to stimulate expression of functional channels is underestimated.
Collectively, C. pneumoniae infection stimulates expression of ISGs via recognition by endosomal TLRs and cytoplasmic RLRs.
Wy14643 also stimulated expression of a number of secreted PPARα targets including FGF21 and ANGPTL4.
In no case did HIC stimulate expression from the HIV LTR (Fig. 1E).
We then directed our efforts to determine whether stress could stimulate expression of VdGARP1.
IL-4 can regulate and stimulate expression of the MCP-1 by human endothelial cells [35].
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