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Previous studies reported that caffeine has many stimulating effects such as increasing sperm motility and inducing acrosome reaction and thus increasing the penetration rate and boar spermatozoa bound to the zona pellucida [ 2].
Besides mechanical effects such as fragmentation of brittle material on acoustic interfaces (ie, glass/air or kidney stone/surrounding tissue), cavitation bubbles (Wolfrum et al 2003) are generated in the propagation medium (ie, water or elastic body tissue), which in turn causes needle-like punctures (ie, leading to stimulating effects such as the generation of action potentials of nerve cells).
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MMP gene expression is regulated at the transcriptional level, controlled by the stimulating effects of cytokines (such as IL-1β and tumour necrosis factor [TNF]-α) and growth factors (such as epidermal growth factor, platelet-derived growth factor, basic fibroblast growth factor and transforming growth factor-β).
On the other hand, it has been reported that estrogen also has stimulating effects on osteoblasts as well by attenuating PTH-induced inhibition of osteoblast proliferation [31, 32].
Creating and liberalizing capital markets, such as the UK's Alternative Investment Market, can have a stimulating effect as well.
Shochat et al. [ 63], and Foley et al. [ 59], proposed models considering both, stimulating effects of G-CSF as well as the cell depleting effects of chemotherapy.
Franchisees perceive stimulating effects as well, but they also see more negative or lack of effects.
Previous reports on nonactivated human cells (i.e., human PBMCs or human monocytic cell line THP-1) revealed that lower concentrations of Cd showed stimulating effects on production of cytokines such as IL-1 β, IL-6, and TNF- α [ 29, 30].
However, such stimulating effects were not consistently observed in both PANC-1 and BXPC-3 cells.
Our results clearly indicated the involvement of chemical factors in the growth inhibitory and stimulating effects of A. altissima against other plants such as alfalfa.
The same sensitization may occur in humans if exposure to stimulants such as Ritalin predisposes children to the stimulating effects of tobacco, cocaine and amphetamines, Lambert says.
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