Sentence examples for stimulating death from inspiring English sources

CCK induces apoptosis by stimulating death signaling pathways in rat pancreatic acinar cells, including caspase activation, cytochrome C release, and mitochondrial depolarization [ 68].

Besides agonistic antibodies the major way to stimulate death receptors is the use of their naturally occurring "death ligands" CD95L, TNF and TRAIL.

It may also stimulate death (Yoshioka et al., 1995; Matute et al., 1997).

The effect of insulin or IGF-I in stimulating cell death and DNA fragmentation H4-II-E cellsuppressedressed by overexpression of regucalcin [ 50].

For the genome, or a society composed of genes, stimulating cell death upon entry or activation of potentially hazardous genetic or epigenetic systems may be more advantageous than accepting them.

We now understand that host immune cells and tissue pathophysiologic "death mechanisms" can stimulate necrosis (death of internal cell organelles) or apoptosis (due to "death programming") cell signalling [ 5].

Many anticancer drugs also induce death by stimulating the generation of ceramide (Claria, 2006; Lin et al, 2006).

In other words, if the cell dies by necrosis, this event leads to pro-inflammatory toxicity that stimulates death of the surrounding cells that have survived the initial stress.

To seek direct evidence on why extrasynaptic activation failed to induce death, we stimulated neurons with different concentrations of NMDA after blocking the synaptic receptors.

In the death receptor pathway, apoptosis occurs upon the activation of caspase-8 stimulated by death receptors in the cell surface, whereas in the mitochondrial pathway apoptosis is dependent on the activation of caspase-9 resulting from the release of cytochrome c from mitochondria to the cytosol.

The complex role of mitochondria in mammalian cell death was highlighted when several studies elucidated resident mitochondrial proteins were able to stimulate cell death directly.