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individuals, of which half were exposed to tropane alkaloid biosynthesis stimulating conditions by co-culture with Agrobacterium rhizogenes.
Little is known about the topology and the coordination of the biosynthetic pathways leading to the variety of tropine and pseudotropine derived esters in the alkaloid spectrum, or about the metabolic dynamics induced by tropane alkaloid biosynthesis stimulating conditions.
Recently is has been shown that α- and β-hederin increase the β2-adrenergic responsiveness of alveolar type II cells (A549) and human airway smooth muscle cells (HASM), respectively, by inhibiting the internalization of β2-adrenergic receptors (β2AR) under stimulating conditions.
Interestingly, the reduced inhibition by somatostatin may partially compensate for the insulin secretion defect, at least in stimulating conditions.
In the rest of the study, 5.5 mM and 16.7 mM glucose concentrations were used as low and high stimulating conditions.
Draining lymph node cells from either control or rHsp65-inoculated mice were harvested on day 21 after immunization and assayed for cytokine secretion under IRBP and rHsp65 stimulating conditions.
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There are several possible reasons for the disparate impact of atorvastatin on CXCL5 expression in non-stimulated and stimulated conditions.
However, the kinetics of calcium accumulation upon TCR stimulation should be measured (including both baseline and stimulated conditions).
The insulin stimulation index was calculated as follows: secreted/total insulin in stimulated conditions vs. secreted/total insulin in resting conditions.
The ROS production was significantly higher in the infected fluid under both the basal (Fig. 4) and stimulated conditions (Additional file 1: Figure S1).
However, in stimulated conditions, hyperglycemia did not increase ROS production of the NADPH oxidase system but accelerated the reactivity of the system (slope of the luminometry curve).
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