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Both radiation therapy and chemotherapy can kill tumour cells by stimulating apoptosis.
The studies conducted seems to suggest that zerumbone induces cell death by stimulating apoptosis better than cisplatin, based on the significantly higher percentage of apoptotic cells in zerumbone's treated cancer cells as compared to cisplatin.
The peptide inhibited RSK activation, stimulating apoptosis of HSC, preventing progression and inducing regression of liver fibrosis.
Therefore, in addition to shortening chronological lifespan and stimulating apoptosis, the failure to efficiently arrest growth in G1 during nutrient depletion contributes to chronological age-dependent genome instability.
The peptide inhibited RSK activation, stimulating apoptosis of HSC, preventing progression and inducing regression of liver fibrosis compared to control mice treated with CCl4.
Noscapine potentiated the anticancer activity of Doxorubicin in a synergistic manner against TNBC tumors via inactivation of NF-KB and anti-angiogenic pathways while stimulating apoptosis.
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This apoptotic effect could be due to either direct toxicity of the E7 protein or to stimulation of cellular immunity which, in turn, would stimulate apoptosis.
(2013) report that 10 µM LPA inhibited proliferation and stimulated apoptosis in hNS/PC cells, seemingly in contradiction to the LPA-stimulated increases in cell growth reported herein.
Furthermore, EGCG may stimulate apoptosis in cancerous cells by negatively regulating the cell cycle to prevent continued division.
The results indicated that the Cortex moutan heteroglycan and curcumin could inhibit colorectal carcinoma (LOVO) cells growth and stimulate apoptosis.
VOAsc (50 100 μM) significantly stimulated apoptosis in both cell lines (170 230% basal, p < 0.02 0.002), but did not affect reactive oxygen species production.
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