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Adiponectin is another adipocyte-derived peptide hormone, able to stimulate the sensitivity of peripheral tissues to insulin, thus acting to enhance insulin sensitivity and protect against conditions of insulin-resistance [ 46].
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Circulating adiponectin concentrations are inversely correlated with fasting plasma insulin (Hotta et al, 2000), and adiponectin stimulates the sensitivity of peripheral tissue to insulin (Yamamoto et al, 2002).
CELM may stimulate the insulin sensitivity via PPARγ2.
BAY 41-2272 directly stimulates sGC and increases the sensitivity of the enzyme to NO, generating significant amounts of cGMP by stimulating the sGC mostly via NO-independent mechanisms [ 38, 39].
TSH stimulates thyrocyte metabolism, Glut1 expression in thyroid cells, glucose trapping, and glycolysis and published data suggest that TSH stimulation significantly improves the sensitivity of 18F-FDG-PET/CT (2).
A cold treatment does not stimulate GA biosynthesis directly but rather increases the sensitivity of a seed to GA.
It plays a pivotal part in adipogenesis, lipid biosynthesis, insulin sensitivity, but has also been demonstrated to stimulate the formation of M2 macrophages.
Restoring insulin sensitivity can be an effective strategy for preventing and treating diabetes, but the only insulin-sensitizing drugs on the market also stimulate the production of lipids (fats), which can lead to a number of serious side effects.
T cell produced TNF stimulates bone resorption directly by potentiating the sensitivity of maturing OCs to RANKL.
51– 54 However, as recently reported by Balogova et al, 55 generalized skeletal uptake in patients receiving bone marrow-stimulating factors (like erythropoietin) could reduce the sensitivity of PET/CT using FCh or CCh; such behavior is not seen in bone-seeking radiopharmaceuticals, such as NaF and bisphosphonates.
6, 7 The sensitivity of Tg can be increased with thyroid-stimulating hormone (TSH) stimulated by either thyroid hormone withdrawal or recombinant human TSH administration.
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