Sentence examples for stimulate the activation of from inspiring English sources

In addition to NGF, many other stimulants have been reported to stimulate the activation of ERK, PI3K and other signaling cascades [6], [18], [26].

In addition, the overexpression of constitutively active RhoA in siVEGF-A-treated cells rescued the inhibition of proliferation, indicating that endogenous VEGF-A-binding NRP1 activated Syx RhoGEF in order to stimulate the activation of RhoA, thereby leading to the degradation of p27.

This conclusion is also supported by direct stimulating effects of the heptapeptide on cultured renal cells to stimulate the activation of NF-κB and related genes.

These results support a model in which Ca2+ is an essential constitutive activator of hBest1, while ATP serves as a coactivator to stimulate the activation of Ca2+-bound hBest1.

As a pro-inflammatory cytokine, IL-18 could stimulate the activation of NF-κB pathway and subsequently synthesize IL-6 and CRP [29].

High levels of chemokines could stimulate the activation of trigeminal nerves and the release of vasoactive peptides, resulting in inflammation [43].

At the same time, overexpression of 4EBP1 reduces the viral mRNA expression yet stimulate the activations of VP1, while the others promote the viral mRNA expression but decrease the VP1 expression at the late stage of infection.

The interaction between BMSCs and myeloma cells also stimulated the activation of NF- κB and p38 mitogen-activated protein kinase (MAPK) pathways.

Further experiments using FSH signaling antagonists identified PKA as an upstream activator of PI3K, which in turn stimulated the activation of AKT.

Moreover, FSH administration not only maintained the morphological integrity of caprine preantral follicles but also stimulated the activation of primordial follicles and the growth of activated follicles in culture [ 38].

Here we show that G-Rh2 stimulated the activation of both caspase-8 and caspase-9 simultaneously in HeLa cells.