Sentence examples for stimulate channel from inspiring English sources

In order to stimulate channel activity we supplemented the experimental conditions with menthol and/or PtdIns(4,5 P2.

In many cases the lipids stimulate channel function or increase insertion of channels in the membrane.

The T294M mutation is the first mutation to be shown to selectively abolish the ability of MgADP to stimulate channel activity in the presence of MgATP.

It is therefore possible that the L164P mutation reduces the efficacy of coupling between SUR1 and Kir6.2, and thereby decreases the ability of MgATP to stimulate channel activity.

At a concentration of 100 µM, these nucleotides have little inhibitory effect at Kir6.2 but stimulate channel activity via SUR1 (Trapp et al, 1997).

Hence, the dependence of N5 activity on tether length suggests that even though N5 does not act as a Gβγ mimic, its ability to stimulate channel activity by affecting cell surface expression requires some degree of proximity to the channel.

Conceivably, the diminishing response in the stimulated channel may at times even fall below the spontaneous firing rate in the opponent, non-stimulated channels, which could generate reversals.

Since the GSK101 stimulated channel currents still displayed a similar desensitization to that observed in Ca2+ containing media, it follows that the desensitization of the channel following GSK101 stimulation is not Ca2+-dependent.

MgADP alone stimulated channel activity to the same extent as for wild-type channels.

As Fig 7B shows, MgGDP stimulated channel activity both in the absence and presence of MgGTP.

Metabolically induced changes in channel activity are produced by altered intracellular adenine nucleotide concentrations, with ATP inhibiting and MgADP (and MgATP) stimulating channel activity [ 9– 12].