Some activities (for example, a progressive jogging program) charge and stimulate adaptation of the cardiovascular system, but do not stimulate an adaptive bone response that would increase bone density [ 51].
We believe that, particularly in the case of chronic diseases, the focus needs to shift to stimulate adaptation to disease and to achieve well-being.
These observations may have significant clinical impact, as conventional chemotherapeutics further stabilize already elevated mutp53 levels, which inadvertently may stimulate adaptation to adverse environments and promote cancer cell survival and chemoresistance.
They also inform more targeted opportunistic monitoring of potential responses of animals during sonar operations and have stimulated adaptations of field methods to consider increasingly realistic exposure scenarios and how contextual factors such as behavioral state and source proximity influence response type and probability.
Conversely, regular exercise appears to produce a hormesis response, whereby the stressor (exercise) induces a transient, systemically oxidative environment that stimulates adaptations enhancing the capacity of tissues throughout the body to neutralize ROS and to more effectively regulate redox balance (see Figure 1).
If patch dynamics does not kill you, it stimulates adaptation to a dynamic habitat landscape which selects for rapid dispersal.
A lower intensity stressor that stimulates adaptive plasticity and regulates the system bidirectionally to restore homeostasis is acting on endogenous processes of adaptation.
Recent findings suggest that brief intense, interval-based exercise interventions may stimulate cardiovascular adaptations and provide protection against future and current CVD [ 40- 45].
65 By challenging the functional reserve in the muscle oxygen diffusing capacity most likely utilised in hypoxia, 91 repeated maximal efforts in hypoxia have the potential to stimulate beneficial adaptations in terms of PCr resynthesis and oxygen utilisation mediated by HIFs at the muscular level.
It is identified that habituation due to the past thermal experience of a long-term living in a specific region could stimulate psychological adaptation.
