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We show that caveolin-1 (Cav1) favors cell elongation in three-dimensional cultures and promotes Rho- and force-dependent contraction, matrix alignment, and microenvironment stiffening through regulation of p190RhoGAP.
A potential advantage of platelet-like nanofillers as nanocomposite reinforcements is the possibility of achieving two-dimensional stiffening through planar orientation of the platelets.
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To test the hypothesis that matrix stiffness affects myofibroblastic activation of PSCs, we have prepared cell-laden hydrogels capable of being dynamically stiffened through an enzymatic reaction.
The CEB model developed for tensile RC members integrates the tension stiffening effect through an increase in reinforcement stiffness.
This sensor employs a novel mass block structure that possesses a specially designed hole pattern and introduces two stiffening beams through them to enhance the dynamic properties and remove the coupled rotational interference.
Recent studies have highlighted the geometrically nonlinear response of structural lattices based on tensegrity prisms, which may gradually change their elastic response from stiffening to softening through the modification of mechanical, geometrical, and prestress variables.
As a frame is loaded in the multiple patterns, the changes in member axial loads affect the frame frequencies and mode shapes in a complicated way through geometric stiffening.
The sensing mechanisms were analyzed through the closed-loop stiffening effect and the enhanced conjugate effect.
Just two or three years ago this development would have reverberated through our political culture, stiffening the spines of social conservatives and causing acida within the diverse life sciences advocacy world, tensions I catalogued in my book, The Body Politic.
Moreover, elevation in plasma [Na+] can induce hypertension independently of EC fluid volume, through mechanisms that probably include stiffening of vascular endothelium [ 42- 46].
Brook appeared to be in complete control but Senchenko demonstrated tremendous spirit, stiffening his rival with a big right midway through the fourth.
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CEO of Professional Science Editing for Scientists @ prosciediting.com