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Oxidation is strictly correlated with the sterilization method: UHMWPE components sterilized with ethylene oxide (EtO) do not oxidize, while those sterilized using high-energy radiation in air (γ radiation or an electron beam with a dose of 25 40 kGy) are known to show high levels of oxidation [3, 6, 7, 8, 9].
The low differences between free radical concentrations in the original samples and sterilized samples indicate the proper sterilization method was chose for caraway, curry, curcuma, and cardamom.
The material for the study was provided by K.P.P.S. Interjarek company (Gołuchów, Poland) where herbs and spices were sterilized by means of NMC® 89 steam sterilization method.
Use of a roughened tibial baseplate had a greater effect on wear magnitude than sterilization method.
To find the ultimate sterilization method for these protein-based materials is rather challenging.
It is found in this work that accelerated aging causes a decrease in fatigue resistance regardless of sterilization method.
Susceptibility to damage processes can be further complicated by choice of sterilization method and shelf aging prior to implantation.
This sterilization assessment protocol proved to be a successful tool to monitor and optimize the proposed sterilization method.
We speculate that the type of sterilization method used may influence cellular responses by altering the surface characteristics.
This work developed a sterilization method suitable for decellularized pericardial scaffolds that could be adopted for in vivo tissue engineering.
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In order to avoid the transmission of pathogenic contaminants and be distributed as sterile biodevices, decellularized valves need to be submitted to proper disinfection or sterilization methods.
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