This approach leads to the specific uptake of the radiopharmaceutical into the bacteria and not the sites of sterile inflammation.
Critical mechanisms and signaling pathways, which trigger necrotic cell death and sterile inflammation, are discussed.
Endogenous nuclear or mitochondrial DNA can also be sensed by cGAS under certain conditions, resulting in sterile inflammation.
Varga, T. et al. Highly dynamic transcriptional signature of distinct macrophage subsets during sterile inflammation, resolution, and tissue repair.
Ebihara, N., Matsuda, A., Nakamura, S., Matsuda, H. & Murakami, A. Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing.
As MaR1 potently accelerated resolution of sterile inflammation and is present in human milk, we assessed its ability to enhance resolution of infection (Supplementary Figure 3c, d).
Montgomery, S. T., Mall, M. A., Kicic, A. & Stick, S. M. Hypoxia and sterile inflammation in cystic fibrosis airways: mechanisms and potential therapies.
Therefore, the role of HSPs and HMGB1 in sterile inflammation and SIRS remains elusive [28, 29].
A tracer capable of distinguishing between microbial infection and sterile inflammation would have clinical value.
Moreover, 99mTc-cefprozil could efficiently differentiate between bacterial infection and sterile inflammation.
Turpentine oil was intramuscularly injected into the left thigh muscle of rats to create sterile inflammation model.
