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Table 2 shows the regression analysis results of the mediation effect stepwise test (Baron and Kenny, 1986).
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Which role do LoCs play in the stepwise testing approach of the ERA of GMOs?
We then considered its relationship with protection goals, the comparative safety assessment and the stepwise testing approach.
Fig. 5 Limits of Concern and the consequence for the stepwise testing strategy in the ERA of GMO own view.
The results are presented in stepwise tests of models with increasing numbers of estimated parameters, starting with empty models.
Fig. 4 Limits of Concern and consequences for the stepwise testing strategy in the ERA of GMO as interpreted from the EFSA guidance [3].
Experimental stepwise tests are run on undamaged and impacted specimens with different combinations of thickness and grade for the outer steel skins and the inner polymeric core.
Since it is likely that, in many circumstances, an animal test cannot be currently replaced by a single replacement alternative method, the development, evaluation and optimisation of stepwise testing strategies and integrated testing schemes should be encouraged.
However, for GMOs, no such validation studies have been conducted so far (see also "The role of the LoC in the stepwise testing approach of the ERA of GMOs" section).
While it could be expected that it induces a particular cautious practice in China, the substantive yardsticks guiding the stepwise testing are not as strict and precautionary as those required by EU legislation.
The stepwise testing of both 1 and the novel A2P/AMP solvent blend is described through a transition process that identifies many of these process and evaluation challenges not often addressed when designing a chemical or catalytic additive for industrial CCS systems, where consideration of solvent chemistry is typically the primary goal.
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