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As DJ joints were not detected by Southern blotting, we deduced that the stepwise order of VDJ assembly for the TCRβDMF is mainly V-to-D rearrangement, followed by VD-to-J rearrangement.
This limited polyUb chain synthesis occurred nonprocessively; i.e., reaction products appear in stepwise order and subsequently disappear in conjunction with the appearance of the next slower-migrating band.
The potential confounders were added to the model in a stepwise order according to their effect on the risk estimate but were kept in the model only if the exclusion changed risk estimate at least 5%.
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This ranking can be used to build a predictive model, without eliminating any variables, using any other machine learning prediction method, in this case and differently from Genuer et al [43], Support Vector Machines [48], inserting the variables stepwise in order to find a good balance between the number of variables and prediction error.
Variables entered stepwise in order: Gender + Age+ Patient status.
Based on this initial MSA, our framework conducts a given number of independent ML tree searches (on distinct randomized stepwise addition order parsimony starting trees) and executes them in parallel to generate an initial set of ML trees.
For the NSF plant tree of life grand challenge project, we deployed the PThreads version (running on a single 48-core node) to perform 100 ML searches (each search starting from distinct randomized stepwise addition order parsimony starting tree) on a real-world DNA alignment (116 334 taxa, 16 079 bp) under CAT and a partitioned model.
It is generally assumed that it acts via a stepwise higher-order oligomerization process and recruitment of histone-modifying activities (Canzio et al, 2014).
In vitro data on Swi6-nucleosome interactions further imply a direct role of Swi6 in spreading along the chromatin fiber through a process of stepwise higher-order oligomerization (Canzio et al, 2011, 2013).
Results of the stepwise multiple ordered logistic regression analysis showed that the number of visits was significantly higher in patients with shorter distance from home to hospital, in those with a more severe burden of overall comorbidity, and in those on pharmacological treatment (Model 1 in Table 2).
Results: When physician-management physician data were added to the use of forward stepwise regression, entry order was abnormal position, nulliparity, birth weight of >4000 g, and physician.
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