The strain tensor, obtained as described in previous subsection, was used to calculate the stress tensor by a radial return algorithm based on isotropic von Mises plasticity, as described by Marth et al. (2016), but without using a stepwise modelling of the hardening relation.
Table 2 presents the stepwise models of this analysis in which the baseline models summarize the effects of different dimensions of parental absence and children's characteristics in relation to child health in Moldova and Georgia (Models 1 and 4).
Based on the information available, we propose a stepwise model of mitotic chromosome condensation that envisions the sequential generation of intra-chromosomal linkages by condensin complexes in the context of cohesin-mediated inter-chromosomal linkages, assisted by topoisomerase II.
The stepwise model of human CRC development and progression proposed by Vogelstein and colleagues [ 12, 13] includes: 1) inactivation of the APC, SMAD4, and P53 tumor suppressors; 2) overactivation of the KRAS oncogene; and 3) development of genomic instability in the form of either chromosomal instability (CIN) [ 12- 16] or microsatellite instability (MSI) [ 16, 17].
Our results could be interpreted as if C2 strain 86 24 is an offshoot of cluster 3, which is in contrast to the established stepwise model of O157.
The nSSR loci were assumed to fit a stepwise model of mutation (SMM), with a mean mutation rate of 10−5 mutations per locus per year.
3. Is the spatial apportionment of genetic variation consistent with a stepwise model of colonization?
Collectively, our data suggest a stepwise model of enhancer activation during adipogenesis.
This hypothesis is in keeping with a stepwise model of progression of CRC.
We describe a stepwise model for the origin of the translation system in the ancient RNA world such that each step confers a distinct advantage onto an ensemble of co-evolving genetic elements.
