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TdPI folds through a stepwise generation of heterogeneous populations of one-disulfide, two-disulfide, and three-disulfide intermediates, with a major accumulation of the nonnative three-disulfide species IIIa.
Yutsis, Levinson and Vanagas developed graphical techniques for representing the general recoupling coefficient as a cubic graph and they describe a set of reduction rules allowing a stepwise generation of the corresponding summation formula.
Details of the stepwise generation of the mutated genomic cDNA can be obtained from the authors on request.
Figure 9 A, B shows the stepwise generation of the filters for this case imitating single detection channel experiment.
Given that both cTECs and mTECs shape the αβ T-cell repertoire, further analysis of the stepwise generation of the cTEC and mTEC lineages, and the regulation of bipotent TEC progenitor development, will be important in informing strategies aimed at regenerating both cortical and medullary compartments of the thymus.
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Stepwise improvements over three generations of device design resulted in an increasing trend in the recovery of FNRBCs.
Dendrimers are synthesized in a stepwise manner to higher generations using a number of chemical reactions, so carrying out the synthesis in a conventional reactor is time-consuming.
Pten protein loss occurred only in the histiocytic portion of tumors, suggesting a stepwise genetic inactivation in the generation of HS.
These stepwise oxidations culminates in ROS generation (Fig. 8).
However, APP can also be processed by an α γ secretase stepwise pathway, which precludes the generation of Aβ (the antiamyloidogenesis pathway).
Therefore, intermediate alleles might rather be considered as predisposing alleles for further stepwise expansion over probably many generations instead of pre-mutations.
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