Sentence examples for stepwise escalation from inspiring English sources
In this study, we established gastric cancer cell lines that were resistant to 5FU by continuous, stepwise escalation of 5FU.
In type 2 diabetes, a stepwise escalation of therapy is suggested along the course and progression of the disease.
The American Diabetes Association and the European Association for the Study of Diabetes have published a joint treatment recommendation with an algorithm for the stepwise escalation of therapeutic steps in the course of type 2 diabetes (52).
Although initial pharmaceutical therapy is with an oral glucose-lowering agent, a steady decline in islet β-cell function results in progressive hyperglycaemia, which requires a stepwise escalation of treatment.
> -wrap-foot> aRatiofof IC50 of 5FU alone to IC50 of 5FU/LV for each cell line In this study, we first established four gastric cancer cell lines with acquired resistance to 5FU by continuous and stepwise escalation of 5FU in the culture media.
If severe ARDS is characterised by profound hypoxaemia that responds to traditional management, our findings demonstrated that a high rate of misclassification occurred because patients were not reassessed after 24 h of usual care when many patients responded to a stepwise escalation of traditional therapies.
Our aim was to test whether stepwise dose escalation attenuated the first dose effect of Nexvax2 in celiac disease patients.
A stepwise dose escalation was performed in order to determine the in vivo maximum tolerated dose (MTD).
CDDP-resistant KB cells, KB/CDDP T), were established by stepwise dose escalation with CDDP in our laboratory.
Cisplatin (CDDP -resistant head and neCDDP -resistantlls were establisheadby stepwise dose escandtioneckth cancer
Instead of starting with diet and/or monotherapy followed by stepwise treatment escalation when failure is achieved, patients should be treated with an initial period of intensive insulin therapy to maximize β-cell recovery and then either continued on an insulin-based regimen or switched to multiple hypoglycemic medications with complementary mechanisms of action.
