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The model is developed by a series of refinements following the stepwise development approach.
It contains rather specific provisions on the stepwise development and testing of agricultural GMOs.
In this paper, the stepwise development of a novel multivalent high-affinity ligand for CD22 is described.
The sophisticated role of the venous system is presented through stepwise development of a prototypical cardiovascular system.
This can prevent writing formal specifications close to the actual implementation, and can thus hamper a refinement-based stepwise development.
Industrial upgrading (IU), the stepwise development of manufacturing skills from simple to more complicated tasks, can be a highly effective approach for late entrants.
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A stepwise method development strategy has been employed to develop a robust HPLC method to resolve several closely eluting structurally related impurities in an active pharmaceutical ingredient (API).
The stepwise formal development of safety critical software is now a well established engineering practice, noticeably in railway systems.
ECM scaffolds stepwise mimicking development of tissues can provide useful models to investigate the interactions between stem cells and ECM during the process of tissue development.
In this paper, we report our recent experience in the stepwise formal development of a real macro-cell, that opens the way to the design of synchronous digital circuits with zero functional bugs.
Stepwise model development is explained below with relevant model equations for each observed PD marker.
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