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Contrary to the stepwise changes of the order parameters in the L12 loop, which forms direct interactions with MLL in binary KIX·MLL and ternary KIX·MLL·pKID, the three-helix scaffold of the binary KIX complexes rigidifies upon binding a single ligand (either MLL or pKID) and shows no further rigidification upon binding an additional ligand molecule to form the ternary complex KIX·MLL·pKID.
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The stepwise change of the reactant stoichiometry in the transient experiments allowed decoupling chemistry (ms timescale) and temperature (s timescale).
This migrating epicenter distribution resulted in the second stepwise change of the b-value, which jumps at the occurrence of the M7.3 event in Fig. 10.
Data from the literature on activation parameters for the electrochemical reduction of O2 in various acid media (concentrated phosphoric acid, trifluoromethane sulphonic acid and perchloric acid) have been treated, using a model of stepwise change of the activation energy.
An almost stepwise change of the reduction peak potential for more than 0.8 V into the negative direction around pH 5 indicate that both reactants have quite different stability and/or structure.
The effect of isothermal stepwise changes of an applied magnetic field in an Ni Mn–In Co metamagnetic shape memory alloy has been studied.
Stepwise changes of functional oxo and amino groups in 1,8-naphthyridines to modify the supramolecular architecture have been carried out.
The dynamic behaviour of a continuous thickener at stepwise changes of solids load has been studied at thickening of unflocculated barium sulphate.
It is shown that these transitions are accompanied by stepwise changes of entropy.
Stepwise mutation models, which allow for stepwise changes of repeat size of alleles, have been extensively used to study MSs.
In this line, Grychtol and colleagues [ 84] proposed a fuzzy logic-based algorithm to analyze EIT images obtained during stepwise changes of mean airway pressure to identify alveolar opening of collapsed regions, overdistension of previously functional areas, collapse of previously opened alveolar regions and the recovery of previously overdistended alveoli.
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