Sentence examples for stepwise altering from inspiring English sources

Subsequent modifications of the minimal promoter moiety of the Ptet promoters followed a rational design strategy, stepwise altering known functional sequence elements within the CMV minimal promoter as used in Ptet-T1.

However, cancer development is a very complex stepwise process involving altered cell functions at many steps, through changing almost all genes in gene expression [ 7, 8].

The stepwise progression from altered hepatocytes to dysplastic nodules, or precancerous lesion, occurs as a consequence of chronic inflammation and genomic alterations, which commonly precede HCC [ 27, 39, 92].

We believe that this stepwise approach does not alter the course of the disease and the end result is patients who are taking multiple antidiabetes drugs and still have not achieved glycemic targets.

The stability of milk miRNAs in the exosomal fraction were examined under the following conditions: (A) pH1.5 for 5 and 60 minutes; (B) pH4 for 5 and 60 minutes, the pH was altered by stepwise addition of 1 N HCL aliquots as required and (C) treatment with RNase was for 5 and 30 minutes at 37°C.

The development of cancer is closely associated with the stepwise accumulation of not only somatic mutations, but also epigenetic alterations that alter chromatin structure and lead to dysregulated gene expression.

Birds altering flight patterns.

Consider altering your look.

Consider altering the environment.

Forcing age, sex, BMI, and hour of blood draw into the stepwise regression models did not alter the reported findings significantly.

For those women in whom knowledge of a likely hereditary cancer syndrome or mutation status might alter their cancer treatment, we suggest a stepwise approach to their genetic assessment.