Suggestions include publishing all papers electronically along with reviews; authors taking steps to encourage replications of their work; and editors inviting replications of important papers.
Israel, he wrote in his blog, wanted the Swedish government to distance itself from the article or take steps to prevent a replication, but that was not how the country worked.
Although the limits of the different replication techniques might be known, the awareness for problems that can arise due to replication steps is quite low.
Our recent findings indicate that ATR and ATM modulate WRN function at defined steps of the response to replication fork arrest.
To duplicate chromosomal DNA, double-stranded DNA must first be unwound by helicase, which is loaded to replication origins and activated during the DNA replication initiation step.
The initial step to evolve units of replications to higher mutation rates was repeated both here and in Takeuchi and Hogeweg (2008).
Here, we analyze the effects of chromatin from small-scale features such as individual histone modifications to large-scale chromosome architecture and the role they play in the various steps of replication.
Cultured cells are often used to study basic steps in virus replication.
These effector-pathways individually block viral transcription, degrade viral RNA, inhibit translation and modify protein function to control all steps of viral replication [4] [5].
Timely PCNA loading and unloading are central for genome integrity and must be strictly coordinated with other DNA processing steps during replication.
