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For RNA measurement, bias can be reduced by aiming to replicate the experimental steps that afford the highest variance from sample to analysis.
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To mitigate antibody probe cross-reactivity, western blotting has become a workhorse tool, a multistep assay that relies on antibody binding for detection, typically after an upstream protein sizing step that affords enhanced assay specificity.
We have developed a novel two-step kNN QSAR modeling approach that affords a successful prediction of acute toxicity (LD50) values from chemical structure for both rats and mice.
It could involve more Libyans in the proceedings, a step that would afford the I.C.C. greater access to victims and give young Libyan lawyers and other professionals experience with a modern system of justice.
At the southwestern corner of the later palace, the west lobby led to the grand staircase of 22 steps, a landing, and another 17 or 18 steps culminating in a small forecourt that afforded entrance to the great court and to a square room immediately to the north.
IMP466 also was labeled in solution using a higher dose of peptide in a two-step, one-pot solution process that afforded the Al18F-IMP466 in 97% decay-corrected yield after HPLC purification [29, 30].
Some China scholars see these moves as a well-planned long-range strategy of establishing its hegemony through salami tactics of what the Chinese call ling chi - or 'death through a thousand cuts.' Over the past two decades, Beijing has taken small incremental steps to assert its claims - steps that countries oppose but cannot afford to get too exercised about, and gradually get used to.
We can safely afford to take the steps I've announced today, steps that are designed to reduce the dangers of miscalculation in a crisis.
Focusing on creating a razor-sharp product even if it doesn't sell, and taking the losses necessary, is a step that they can afford to take.
Emphasizing the "words for words" and "action for action" solution, China has tried to establish a clear, step-by-step itinerary, an itinerary that affords equal import to ending North Korea's nuclear activities and satisfying North Korea's economic and security needs.
While unsupervised integration has been shown to be an effective initial analysis step, it is supervised integration that affords the greatest advance to biological understanding (1).
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