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The system was simulated on the fast time-scale during T = 10, 000 time steps of size d t = 0.01.
In practice, the PDE is replaced by a discrete-time (backward Euler) approximation with time steps of size Δ t = 0.01 ; note that the final time is T = 1 and that the number of time steps is n t = 100.
xMAN scans the reference genome using a sliding window of size N (query sequence length) at steps of size 1.
Were we to take an average over the three patients, we would have a step function with steps of size 1/3 at the observed change points.
MapNext scans the reference sequence using a sliding window of size equals to k-mer size at steps of size 1.
This is because if one took k steps of size s, then irrespective the direction each step is taken, one would end up exactly s times as far away as if one had taken the same k steps of size 1.
Similar(51)
The purification was done with three altering steps of size-exclusion chromatography (PD10, GE Healthcare Life Sciences, Little Chalfont, Buckinghamshire, UK) and with spin-column centrifugation (Ultracel-50, Amicon, EMD Millipore, Billerica, MA, USA).
In practice, the PDE is replaced by a discrete-time (backward Euler [30]) approximation with time-steps of size Δ t = 0.005.
This integration is carried out with a fixed time step of size 2.5 days.
If the conditions are fulfilled, the probability that the reaction takes place during the next time step of size Δt is determined.
Briefly, synaptic vesicles were released from synaptosomes by osmotic lysis, and were further purified by rate-zonal sucrose gradient centrifugation and a final step of size exclusion chromatography on controlled pore glass beads.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com