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He did, I believe, put in two or three new sort of steps of regulation, if you like, but never reported back that there was more hacking than we'd been told.
Murdoch said a News of the World editor was appointed – referring to Colin Myler, although he did not name him at this point – "with specific instructions to find out what was going on". "He did, I believe, put in two or three new steps of regulation but never reported back that there was more hacking than we had been told".
One possible explanation is that those people, who were very intrinsically motivated and had internalized it as a value in itself, were critical towards further steps of regulation.
It is also involved in crucial steps of regulation of gene translocation (Nagy and Rigby 1995).
Therefore, NF- κB is increasingly recognized as a crucial player in many steps of regulation of inflammatory responses.
Gene expression is controlled at many different levels but control of transcription is one of the main steps of regulation.
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Access to the nuclear compartment might be a first step of regulation prior to activating target promoters.
It should not be a surprise if such an important step of regulation in the life of a neuron (such as midline crossing) is under control of multiple mechanisms.
Another step of regulation for this cytokine is at the post-translational level where effectors such as extracellular ATP activate caspase-1 that cleaves pro- IL-1β to its mature form, thereby releasing it into the medium.
Pausing of transcription is an important step of regulation of gene expression in bacteria and eukaryotes.
To this end we investigated the first step of regulation by adjustment of transcript levels, that represents the basis for translation, modification and ultimately signaling output.
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