This first step of observation allowed to get information about the number of pictorial layers, its set of features and its thickness.
The steps of fluorescence observation were executed according to the previous protocol (He et al. 2016).
We followed a two-step method of observation and validation to document the process to request and collect OI.
A preloading unloading reloading process with step-by-step observation of the initiation, extension and formation of microcracks on the specimen surface with increasing compression load is described in detail.
Performed using a series of steps: observation of behaviors (score +4 to 0), followed (if necessary) by assessment of response to voice (score -1 to -3), followed (if necessary) by assessment of response to physical stimulation such as shaking shoulder and then rubbing sternum if no response to shaking shoulder (score -4 to -5) [39].
Performed using a series of steps: observation of behavior (score 1 or 2), followed (if necessary) by assessment of response to voice (score 3), followed (if necessary) by assessment of response to loud auditory stimulus or light glabellar tap (score 4 to 6) [35].
Each of the sub- system also had four operational steps of planning, action, observation, and reflection.
The first step consists of observations from clinical or standard non-clinical toxicology studies, leading to the suspicion of immunosuppression: i.e. increased infections, increased incidence of neoplasias, abnormal results of complete and differential blood count (CBC and DBC) or serum immunoglobulins.
At each step of an observation program, a "sensor control" command (TAKE_IMAGE, for example) and an "image operation" command (IMAGE_SUB, for example) can be performed in parallel.
In all models, we included a random intercept for the time step of each observation to control for possible autocorrelation among the data points.
