Sentence examples for steps of initiation from inspiring English sources
Further, we could also distinguish the individual stages based on the sequential steps of initiation, propagation, and integration of intracellular signal transduction cascades (see Figure 7A).
The fact that these latter mRNAs display a lower than average TE in WT cells and benefit from the absence of eIF4G seems to indicate that they function inefficiently at steps of initiation not significantly enhanced by eIF4G.
However, the generalizations that early steps (survival in the circulation, arrest in the microcirculation, extravasation) are efficiently completed, while later steps of initiation and persistence of growth after extravasation are inefficient and variable depending on the cell line and organ, seem to be consistent.
This dependence is consistent with a significant role for eIF4G in stimulating one or more steps of initiation for the most efficiently translated mRNAs in the cell, presumably the activation of mRNA for recruitment of the 43S PIC, scanning the 5'UTR, or start codon recognition.
A peak of GN activity was observed on the stance side just before heel on like in the first step of initiation.
Several studies indicate this nucleotide is important in decoding genetic information, particularly at the step of initiation [ 21, 22, 52].
Similar to hNAP1 (see Fig. 1e), SET enhanced activated transcription during the PIC assembly step of initiation (Fig. 3c).
In contrast to formation of synuclein inclusions in neurons, we did not find similar inclusions and deposits in astrocytes, although glial accumulation of α-syn was described previously, especially at the step of initiation of NDDs [ 24, 25].
Recently it was shown that the mammalian PABP is involved in key steps of translation initiation and might well be regarded as a canonical translation initiation factor [25].
By separating the steps of translational initiation into ribosomal recruitment, ribosomal positioning and ribosomal translocation, we found that the mutated IRES elements could be grouped into two classes.
Many evidences indicate that their deregulation is associated to several steps of cancer initiation and progression.
