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In order to study the role of the neck domain of myosin in muscle contraction, we measured the steps of individual myosin II molecules engineered to have no neck domain (light chain-binding domain) by optical trapping nanometry.
Cope's suggested mechanism for this action was a "steady progressive development of organization" through what Cope termed "a continual crowding backward of the successive steps of individual development".
Diffraction-limited protein subunit stoichiometry estimation can be performed by observing the bleaching steps of individual fluorophores attached to the subunit molecules.
The multiple alignment problem is then reduced to to subsequent alignment steps of individual sequences to a growing multiple alignment graph.
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We paid attention to catalog completeness and performed a completeness check as a preprocessing step of individual analyses while referring to a comprehensive analysis of M c in Japan (Nanjo et al. 2010).
Preimplantation development is the first step of individual life in mammals.
Then, a replication step of individual genotyping was conducted in an independent cohort of 259 cases and 288 controls.
After quality control filtering and SNPs ranking based on a false discovery rate (FDR) below 5%, we performed a replication step of individual genotyping to validate the top-ranked SNPs in an independent cohort of 259 endometriosis and 288 controls.
The probability q of performing the same task in two subsequent time steps is a measure of individual specialization.
Instead, the fear is that Europe's strategy so far — painfully drawn out step-by-step rescues of individual countries — has failed to calm the markets.
The conclusions are made after detailed step-by-step analysis of individual features and functionalities required from industrial controllers.
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