Sentence examples for steps of differentiation from inspiring English sources

These results suggested that CD4SP CD25+Foxp3− thymocytes, which develop independently of IL-2 and IL-15 (Marshall et al., 2014), are the Treg-precursors that require IL-2 or IL-15 for their final steps of differentiation.

The above data suggest that HP1γ may be involved in the very early steps of differentiation, during the commitment process.

Taken together, a coherent cortisol- and IBMX-mediated repression of a few nuclear receptor genes is responsible for the first regulatory effects during early steps of differentiation.

During vertebrate neurogenesis, a cascade of expression of proneural and neuronal differentiation genes encoding bHLH transcriptional regulators, such as Neurogenins, NEUROM and NEUROD1, regulate consecutive steps of differentiation (reviewed in [27], [28] [30]).

Using the technology described in this report, transcription factors can now be used to define populations emerging from human Embryonic Stem Cells, filling an urgent need to classify intermediate steps of differentiation.

To verify whether the differentiation protocol induced rMAPC commitment to intra-embryonic tissue, DE, and then hepatic cells, or merely to VE or PE, which also express a number of presumed hepatic genes [39], we further analyzed the initial steps of differentiation of rMAPC and compared this with the initial steps of hESC differentiation.

We conclude that some of the tumour cells have the double-positive keratin phenotype of the ERα/BMI1 cells grown in vitro, whereas others differentiate to single-positive cells that may represent a step of differentiation towards a luminal or myoepithelial fate, but with a strong tendency for the latter to progress to asquamous phenotype.

Each step of differentiation is regulated by intrinsically programmed mechanisms as well as by extracellular signals.

The loss of H3K4 methylation appears to be a key step of differentiation (Mikkelsen et al., 2007).

Now we introduce definitions for higher-order derivatives based on the selection of derivative type in each step of differentiation.

The second step of differentiation involves identifying negative traits of your early caretakers and seeing how you may be acting these traits out in your own life.