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An individual miRNA can regulate dozens of distinct mRNAs, involving different steps for regulating the metastasis of breast cancer cells [5], indicating the important role and multiple functions of miRNAs in control of tumor progression.
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One hundred-nanometer nanopore diameter was recognized as the transition step for regulating the ALP activity in the cells.
Moreover, a bifurcation analysis identified translocation of pSTAT1 dimers to the nucleus as a critical step for regulating the dynamics of type I IFN pathway in the first steps, which may be important in defining the response to IFN-beta therapy.
More interestingly, studies in recent years also suggest that 3' end processing could serve as a robust step for regulating gene expression in higher eukaryotes by means of alternative polyadenylation (APA), with which the same gene could produce multiple transcripts with varied stability, special RNA motifs, and coding capacities [ 9- 11].
Among these TFs, GATA2 has been implicated to be critical for regulating multiple steps of hematopoiesis in mouse models.
Yet, the existence of non-functional Stim1 Orai1 coupling in a physiological context or the dependence of CRAC channel clusters on a third protein for regulating the final steps in SOCE activation has not been previously speculated.
Congress needs to step in and clarify the authority and responsibility for regulating the products of biotechnology.
If, as expected, Republicans go after the EPA for regulating greenhouse gas emissions without congressional authorization, government regulators can testify that the agency is ready to step aside when the lawmakers meet their responsibilities.
Although the molecular mechanism underlying how a decrease in ΔΨm activates Parkin has yet to be completely elucidated, suppression of the autoinhibitory mechanism (Chaugule et al. 5) and ubiquitin thioester formation at Cys431 of Parkin (Lazarou et al. 20) (M.I., K.T., and N.M., unpublished data) is thought to be a critical step for up-regulating the E3 activity of Parkin.
It also provided the basis for the first steps toward regulating emissions from new power plants, and, possibly, further steps requiring existing plants to reduce global warming pollution.
This summer, city council took steps toward regulating the 120 or so dispensaries that exist by making them apply for city-issued licenses at a cost of $30,000 [ $21,000USD] for retail shops and $1,000 [$700 USD] for Compassion Clubs.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com