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Also, the factors affecting the initial transformation steps and selection are being optimised, to avoid the production of chimeras.
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The screening steps and study selection procedure are shown in Figure 1.
This occurs when the fitness reduction in the absence of mutant alleles is small, that is, n and σ are both large (many steps and weak selection).
The more stringent threshold used in the subsequent steps and repeated selection process minimized the number of false positives remaining in the index.
The criteria for time step cutting and selection are usually based on heuristics that limit the allowable change in the solution over a time step and/or NR iteration.
The idea of evolutionary algorithms is based on the generation of new parameter sets by random variation of an existing parameter set with adapted step size and selection of a set with better fitness.
The parent mutants had more mutations than the transformants (Table 1), which suggests that long term step-by-step selection and growth may require additional mutations or that spurious neutral changes are occurring during the selection of resistance.
Filter methods select features as a preprocessing step and feature selection part is independent of a machine learning algorithm (classifier).
Then, the next population is reproduced after crossover, CEP (steps 04 11), mutation and selection.
The method is based on extrapolation of the two-step explicit midpoint rule and incorporates adaptive time step and order selection.
A single λ Red mediated recombineering step and subsequent selection for Kan resistance accomplishes the extension since the Kan gene can be maintained as a permanent part of the backbone.
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