When the total conductance gain of the synaptic input was incremented in small steps, spikes in specific locations were emitted with gradually decreasing latency, and the relationship between the conductance and latency was accurately fitted with a monoexponential.
In each resampling step, spike responses of randomly chosen units were drawn based on the measured firing probabilities, and the log-likelihood function was computed for each neuron.
The comparison process relies on four steps: gene list analysis, simulations, spike-in data and re-sampling.
Our comparison process relies on four steps (gene list analysis, simulations, spike-in data and re-sampling) to formulate comprehensive and robust conclusions about test performance, in terms of statistical power, false-positive rate, execution time and ease of use.
Further, they added spike-ins during the RNA isolation step, while we added the spike-ins after the polyA isolation step.
To verify the efficiency of the hybridization step we examined the results of the hybridization spike-in controls provided for the Affymetrix GeneChip (QC1).
We describe BisQC, a step-by-step method for multiplexed bisulfite-converted DNA library construction, pooling, spike-in content, and bioinformatics.
Airlines have long taken steps to guard against spikes in fuel prices, usually buying options to acquire fuel at set prices.
Similar results were observed in 6/6 FSIs, in which either serotonin or α-methyl-5-HT had induced, per se, subthreshold depolarizations; in all cases current steps elicited significantly more spikes in the presence of serotonin or α-methyl-5-HT than in control solution (P < 0.001; calculated on number of spikes elicited by at least 10 steps in each experiment for each pharmacological condition).
In contrast, in vitro produced RNA spike-ins are independent of the biological process and can act as controls for both the RT and qPCR steps [ 13, 16].
