In this model, NPR3 and NPR4 binding to SA triggers the Cullin 3 ubiquitin E3 ligase-mediated NPR1 degradation, which is an essential step of NPR1 function [ 19].
(A ) Cartoon of step function of ligand delivered to immobilized cells in simulation to test response dynamics.
Molecular dynamics simulation of a helix-turn-helix motif representing the intracellular TM1-2 domain revealed alterations in backbone conformation, indicating an increased flexibility in these mutants that paralleled changes in elementary steps of channel function.
The major integrins and respective ligands that mediate these steps of EPC function will be discussed in detail in the present review.
In the case of Step function, Lipschitz exponent of 0 correspond to the discontinuity and also the function is non-differentiable as well.
The method, called Binarization across Multiple Scales, is based on the computation of a series of step functions, detection of the strongest discontinuity in each step function and the estimation of the location and variation of the strongest discontinuities.
We consider an approximation of Heaviside Step function of the form: HStep z)=-0.5left[ tanh left(l zright pm 1right]=HS (7 where l is the rate of change between the maxima and minimum of the function.
The annotation step of Blast2GO assigned functions to 18,715 (60%) of unigenes.
Second, we find evidence that the sanction step of electoral accountability functioned only weakly.
