The structural break is related to the unusual value of the level disturbance of the series and is modeled by a step intervention variable which is zero before the event and one after.
Step by step, intervention by intervention, an official Millennium Villages Handbook prescribed the course of action to be followed by "change agents" assigned to each village.
Antidepressant medication was not an option in treatment pathway 1, but could be considered after a first step intervention had not resulted in sufficient treatment response.
On these bases, we resolved to monitor also non respiratory parameters and to consider the telephonic interview as a second step intervention driven by changes in monitored parameters.
On the cusp of this change, we sought to begin to answer some important questions and concerns through the OpenNotes study, using a simple, one step intervention.
The evidence-based five step intervention within emergency departments to implement clinical pathways will be a combination of processes proposed by Doherty & Jones[ 14] and Kinsman et al.[ 7].
