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With carefully designed step-by-step modifications of innovative vaccine formulations, T cell vaccination can be optimized towards the goal of inducing therapeutic immune responses in humans.

The step-by-step modification of SPE is also calculated by electrochemical impedance spectroscopy (EIS) and shown in Fig. S1.

Dynamic contact angle (DCA) measurement and X-ray photoelectron spectroscopy (XPS) analysis confirmed that the step-by-step modification process was successful.

This paper reports the step-by-step modification of the class of FE models and the selection of a representative model class based on the set of ambient vibration data obtained from multi-setup field tests.

The parameterized mechanical model is proposed to optimize chisel-edge grating ruling tool parameters, eliminate corrugated grating lines, improve surfaces roughness of blaze plane, and reduce complex fabrication works such as step-by-step modification of tool guide angle.

Experiments show that our proposed method is an effective way to solve the corrugated line and fluctuating problems on grating grooves, and can avoid complex and time-consuming technical operations such as step-by-step modification of tool guide angle.

The controlled step-by-step modification of the surface chemistry allowed to assess the influence of individual nitrogen surface groups in the electrochemical performance in 1 M H2SO4 of the carbon materials.

Therefore, in order to modify the surface and interlayer of ZrP nanoplatelets differently, a step-by-step modification method should be developed, and a feasible way to achieve this strategy is to modify and protect the outer surfaces of the pristine ZrP nanoplatelets through covalent bonding first, leaving the interlayer untouched for further intercalation.

Step-by-step modification of the original model led to the model presented in Figure 2. We retained having seen the decision aid or not in the modified model despite its insignificant effect on treatment decision, because of its prime role in the research questions formulated.

Go step by step.

Below is a step-by-step list of the modifications made in the revised manuscript.

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