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Although we are cognizant of the potential limitations by using whole-brain homogenates rather than region-specific specimens (that are of relevance to PD pathogenesis), we purposefully sought to minimize any introduction of inaccuracies stemming from variability in tissue dissection and to accommodate a larger number of animals in our quantitative assays.
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Natural uncertainty stems from variability of the underlying stochastic process.
Then, to illustrate the statistical fundaments for the transcriptogram method, we consider gene expression from different microarray experiments and calculate the variance stemming from the variability in the technique and then that originating in the biological variance.
The other three dimensions (i.e. continuity, coordination, community orientation) show that majority of total variability stems from the variability between FPs.
Additionally, the use of blinded investigators and independent adjudication may reduce some of the imprecision stemming from subjectivity and variability among observers [ 41].
The variability in relationships between soil and topographic characteristics with depth may stem from spatial variability in the rate of decline of hydraulic conductivity with depth.
Such wide-ranging results stem from underlying variability in the mediating factors, such as time-since-introduction, rates of invasion, relative changes in plant functional and structure types, and environmental filters such as soils and climate.
The primary issues with clinical PRP use currently stem from the variability in its use.
A uniform probability of σ (default: 5%) is assumed for any mismatch between a read and a genome, which can stem from genome variability and sequencing errors.
This disparity in the mode of inheritance predictions possibly stems from the variability in the onset of the disorder and the classification of dogs as "unaffected" in the statistical analyses when in fact the dogs have not yet expressed the disease.
Such results raise the question of whether inter-neuronal dynamics of spiking patterns stems from intrinsic variability of the hippocampal network and its constituent neurons, or whether they reflect extrinsic changes in hippocampal modulation by higher-order brain structures, adaptations to environmental changes, or subtle changes in animal behavior states.
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CEO of Professional Science Editing for Scientists @ prosciediting.com