The real impact stems from its effect on the oil market.
In vivo and in vitro studies [ 15] have indicated that the biological effects of DPA mainly stemmed from its effects on eicosanoid production, endothelial cell migration and gene expression related to lipogenic and inflammatory genes.
Given that stability of these Gα subunits depends on their complex formation with Gbg (Kolesnikov et al., 2011; Lobanova et al., 2008; Nikonov et al., 2013), the role of PhLP1 in stabilizing Gαt1 and Gαt2 is likely indirect and stems from its effects on Gβγ complex assembly.
Dr. Willett said the mechanism behind weight training's beneficial effect on diabetes most likely stems from its effect on insulin receptors.
Controversy surrounds whether metformin's antitumorigenic benefits stems from its indirect effects via decreasing circulating insulin and glucose levels or its direct effects in tumor cells via AMPK activation and inhibition of the mTOR pathway.
The five decade prolongation of the "blockade" has allowed every setback we've suffered to be explained as stemming from it, justified by its effects.
For Davidson, then, it makes no more sense to ask whether an event had a particular effect in virtue of being mental or in virtue of being physical than it would to ask whether its effect stemmed from its being described in English or in German.
Its antitumor effects stem from its capability to methylate DNA at the N-7 or O-6 position of guanine, thereby damaging the DNA and causing cell death (Srivastava et al., 1998; Hegi et al., 2004; Mutter and Stupp, 2006; Kim et al., 2010; Poteet et al., 2013).
IL-8 proangiogenic effects additionally stem from its ability to inhibit the apoptosis of endothelial cells [ 49].
The mysterious element of shell shock, one that preoccupied practitioners and commentators alike, stemmed from its capacity to visit its damaging effects without leaving obvious signs of physical trauma.
False positives stemming from this effect prevent the standard t-statistic from serving as a reliable or useful test of which genes are truly regulated.
