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The exogenous SDF-1 alpha could enhance the stem cells proliferation, chemotaxis and migration, and the expression levels of related genes were significantly elevated in LESCs and mesenchymal stem cells (MSCs) in vitro.
Furthermore, histamine was shown to have a role in regulating neural stem cells proliferation and the expression of the H1 receptor was shown to favour neuronal fate [39].
Even though intensive research has been made, the basic mechanisms of plasticity and/or the molecules regulating stem cells proliferation and differentiation are not completely determined.
NSCM containing FGF-2 and EGF promotes neural stem cells proliferation, while repressing their differentiation into any type of neural cells.
More recently, it has been reported that target disruption of the klf6 gene caused early embryonic lethality and severely impaired embryonic stem cells proliferation [22].
The essential requirement of the EGR-1 site in prep1.1 expression is interesting because EGR-1 factor is required for hematopoietic stem cells proliferation [20].
Similar(36)
Stem cell proliferation speed is associated with aging.
Likewise, in mammalian systems, MELK is essential for organogenesis, stem cell proliferation, and cell cycle regulation.
Nucleostemin (NS) is a nucleolar protein regulating stem cell proliferation and pluripotency.
Adult rabbit myogenic stem cell proliferation tests show artificial scaffolds to be applicable for biomedical practice.
The functional biomaterial can stimulate stem cell proliferation and chondrogenic differentiation during in vitro culture.
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CEO of Professional Science Editing for Scientists @ prosciediting.com