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ESCs can serve as a potential research model for tissue development, cancer formation and metastasis, phenotype commitment, stem cells based therapy, gene therapy strategies and drug design [4].
Although therapeutic administration in animal models of acute renal injury suggested that BM stem cells based therapy may improve the recovery of both glomerular and tubular compartments, the suitability of these cell tenants for their new home in kidney has not been well investigated so far.
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In stem cells based therapies, the purity of the product (the percentage of stem cells within the cell culture) is crucial for the outcome [ 24- 26].
Stem cell based therapy has been considered as the most promising therapeutic strategy for a range of debilitating diseases (Reynolds and Lamba, 2014).
There is a great possibility that the superior adhesion and proliferation of stem cells, including nerve stem cells, on a nanofibrous scaffold will be able to facilitate stem cell based therapy clinically.
Various cell types including neural stem cells, mesenchymal stem cells (MSCs) and immortalized stem cell lines have been used for stem cell based therapy in experimental settings, as well as clinical research of stroke in an anticipation that it may improve the disease pathology.
We propose the clinical program of stem cell based therapy for XLA should be started in the very near future.
Stem cell based therapy provides a promising treatment option for DMD since fusion between healthy stem cells and dystrophic myoblasts restored dystrophin expression in vitro and in vivo [ 12, 13].
Although the stem cells collected as SP cells possessed valuable characteristics for stem cell based therapy, the important factor in tissue engineering is to harvest the greatest number of cells with the highest potential while minimizing the amount of mesenchymal tissue needed, for less-invasive treatments.
So far, mice offer as an unrivalled tool for understanding about reprogramming machinery and improving methodology in the field of stem cell based therapy, but their size, physiology, and reduced lifespan make them inadequate as an animal model to test for safety and efficacy of therapy.
Stem cell based therapies hold promise for the obstetrician and gynecologist.
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