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Few noticed publication of the N.I.H.'s official stem cell registry in November, which listed 71 separate lines.
I will direct the National Institutes of Health to establish a national human embryonic stem cell registry.
At a small scientific meeting on stem cells in November 2002, I heard a senior N.I.H. official privately concede that the stem cell registry was "misleading".
Later that month, with no public announcement, the institutes drastically amended the stem cell registry, cutting the list to just nine cell lines.
First, Mr. Bush will an announce that the registry of embryonic stem cell lines eligible for research with federal tax dollars will be reconfigured as the "human pluripotent stem cell registry," a change intended to allow other types of stem cells to become eligible for federal financing if they have the same properties as embryonic stem cells.
"Once they're posted, NIH is basically out of it," says Judith Greenberg, who's in charge of setting up the stem cell registry.
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For controls, 1,398 subjects from unrelated hematopoietic stem cell donor registry of Korean Network for Organ Sharing (KONOS) were included.
However, the required sophisticated sample preparation steps and associated costs make that approach currently more attractive for patient samples than for cost-sensitive high-throughput stem cell donor registry typing.
Nevertheless, we believe that the results of our study are unlikely to be affected by systematic errors such as population stratification because the source of our controls, the unrelated hematopoietic stem cell donor registry of the KONOS, represents the whole Korean population rather than certain social groups within the population.
In the first phase of the present study, estimated HLA haplotype frequencies in stem cell donor registries of Finland and its neighbors Sweden and Russia were calculated using the algorithm of the German National Bone Marrow Donor Registry (ZKRD) and their frequencies were compared with one another and also with that of Germany.
Its broad goals are to promote harmonisation between worldwide stem cell donor registries and cord blood banks and encourage uniformity of practice based on internationally accepted standards.
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