Sentence examples for stem cell proliferative from inspiring English sources
It is clear that p63 will have a major contribution in epithelial cell development through its regulatory impact on stem cell proliferative potential [6].
In these tissues, spatially organised stem cell, proliferative and differentiated compartments create a "gradient" of cell differentiation.
This observation provides a 'proof of principle' that stem cell proliferative power (self-renewal) and tumor risk are inversely related.
H2B-GFP and BrdU have been used previously to study muscle stem cell proliferative kinetics (Schultz, 1996; Shinin et al., 2006; Chakkalakal et al., 2012; Rocheteau et al., 2012).
These control mechanisms are poorly understood, but one possibility is that stem cell proliferative activity is influenced by position in relation to more differentiated progeny, to the basement membrane and to stromal cells.
Based on our observations that pharynx regeneration triggered a localized stem cell proliferative response, we isolated a plug of tissue surrounding the pharynx wound site in order to enrich for those transcripts most directly relevant to this process.
(2010) studied the effect of radiation doses ranging from 2 to 20 Gy on adult human dental pulp stem cells proliferative potential and the associated molecular pathways.
These sections represent the stem cell and proliferative functional zones, and the data suggest butyrate may promote the deletion of damaged stem cells and daughter cells.
Recently, dPGC-1 upregulation in stem and progenitor cells of the digestive tract was shown to preserve intestinal stem cell (ISC) proliferative homeostasis and extend lifespan [ 17].
Numerous studies have documented the presence of ALDHbright cells in several adult tissues and demonstrated that these cells carry significant stem/progenitor characteristics including stem cell markers, proliferative potential, sphere formation, clonogenicity, and multilineage differentiation.
Among the most discussed targets of metformin are AMPK activity and AMP-related signaling, glycation reactions and glycation end-products, mitochondrial membranes, reactive oxygen species generation, epigenetic mechanisms, pluripotent stem cells, cell proliferative senescence and mTOR pathway [ 7, 71, 73- 77].
