The relationship between the APACHE II predicted mortality and log hazard of death was non-linear with a steep effect when the APACHE II predicted mortality was less than 10% and a smaller effect when it was more than 10%.
Its anticipated impact on the outcome in an analysis is a steeper exposure-effect gradient, given a true effect.
Post-hoc tests revealed that there was a steeper Ratio effect in the accuracy data in the incongruent trials (p < 0.0005 between ratio 1 2 and ratio 3 5; and p < 0.0002 between ratio 1 2 and ratio 2 3), than in the congruent trials.
Receptor-mediated uptake of the CCK2 compound PP-F11 in tumours shows a steep saturation effect with increasing amounts of peptide.
In both the cynomolgus monkey and in the rat studies, a steep dose-effect relationship for PFOS was conspicuous.
The Mahler and Brahms symphonies, naturally, were more fully steeped in this effect, and by the end of the second program it had come to seem almost a quirk.
Similarly, will payers recognize that while the upfront costs of such treatment may be steep, the overall effect on patients' well-being can save the health care system significant dollars?
Overall, the study shows that current load dominates for most of wave and current conditions analyzed; yet, for large and steep waves, its effect is of similar importance as the current load.
MP analyses were performed using PAUP* 4.0b10 [37], with the following parameters for the heuristic search: 1000 random addition replicates holding 100 trees per replicate, tree-bisection-reconnection (TBR) branch swapping and the options Multrees and Steepest Descent in effect.
All parsimony analyses were conducted using Fitch parsimony [59] with equal weighting of all characters and of transitions/transversions. Heuristic searches were replicated 1000 times with random taxon addition sequences, tree bisection reconnection (TBR) branch swapping, the options MulTrees and Steepest Descent in effect and holding 10 trees per replicate.
