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In the steady state, presentation of these self-antigens should sustain tolerance.
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The stimulus s from Equation 12 uses a sine signal as a basis for stimulating both the noise reduction subsystem as well as the transient noise reduction subsystem: while a steady-state presentation of the sine signal would be sufficient for triggering the noise reduction, the dramatic change of the sine amplitude at time T1 is required to trigger the transient noise reduction.
In this study, we confirm that antigens targeted to DNGR-1 in the steady state can be presented on MHC class II molecules, and we show that this presentation is restricted to CD8α+ DC.
The basic paradigm for peptide-induced tolerance in naive T cells is that antigen presentation by steady state DC leads to an abortive activation and T cell death due to insufficient survival signals [ 12].
The reduced susceptibility of the SDE T5 to tolerance induction likely reflects the relatively short half-life of T5/Db complexes 20, 30, resulting in diminished steady-state epitope presentation levels and a failure to induce negative selection 27.
In vivo, under steady-state conditions, presentation by splenic DC of apoptotic cell-derived peptides loaded in MHC class-I or -II molecule leads to clonal deletion of Ag-specific CD8 or CD4 T cells, respectively, and generation of Ag-specific regulatory T cells (Treg) [ 55– 58].
The presentation is restricted to open systems operating in steady state.
Following the presentation of the theory of powder formation in steady state electrocrystallization, some equations based on the linear instability theory in non-steady state deposition under diffusion control were derived; the galvanostatic case was then analysed using the theoretical equations obtained here.
According to these experimental findings, first we fed 5-Hz Poisson spikes into MFs for 1 s prior to the CS presentation in order to set the network activity to a steady state.
This paper deals with the presentation of the developments of an in-house code created for the steady state thermal-hydraulic analysis of helical coil steam generators.
In this article, we describe an "interleaved silent steady state" (ISSS) sampling scheme in which we rapidly acquire a set of EPI volumes following each silent stimulus presentation period.
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