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Despite all existing pharmaceuticals aiming at effectively reducing LDL cholesterol, the steadily increasing prevalence of coronary heart disease (CHD) worldwide shifted focus on HDL as an alternative therapeutic target for the treatment of CHD.
The steadily increasing prevalence of diabetes constitutes a major health problem.
We fully share their concern that we should try to keep middle-aged people as active as possible despite their health concerns – in particular, with the steadily increasing prevalence of knee osteoarthritis.
Introduced at the turn of the century, orally administered tyrosine kinase inhibitors (TKIs) have transformed the treatment of chronic myeloid leukaemia (CML), changing it from a comparatively rare but fatal cancer in non-transplanted patients to a long-term condition with a steadily increasing prevalence.
Thus, though prevalence was also higher in patients who have undergone surgical procedures with little exposure to blood, these patients showed steadily increasing prevalence with age and higher prevalence in males suggesting a connection with age instead of with the medical procedures themselves.
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Type 2 diabetes is a disease with a high social and economic cost, and is steadily increasing in prevalence (see Disease overview section).
Over the past 3 decades, its use has steadily increased because of increasing prevalence of β-lactam-resistant nosocomial pathogens, particularly, methicillin-resistant Staphylococcus aureus (MRSA) and coagulase-negative staphylococci (CoNS) (2, 3 ).
Cancer survivorship has steadily increased in prevalence since the mid-1970s [ 1- 3] and currently there are over 13 million survivors in the United States alone [ 3, 4].
Insulin and sulfonylurea use steadily increased in prevalence from the 1st to 3rd trimester (16.5% and 3.3% to 33.0% and 7.5%), while metformin and TZD use decreased (11.4% and 1.6% to 3.8% and 0.2%).
ES is a full arrhythmic emergency, its prevalence steadily increasing along with the number of implantable cardioverter-defibrillator implanted every year in developed countries.
Specifically, testing volume appears to be steadily increasing, while the actual prevalence has plateaued.
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CEO of Professional Science Editing for Scientists @ prosciediting.com