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The risk of metastasis in oral cancer patients is associated with the status of copy number alterations at chromosome 3q, 8p, 8q and 20.
Quantitative real time PCR (qPCR) was used to validate seven genomic regions detected by the three methods and representing different predicted status of copy numbers.
Ten putative CNVRs were selected, and represented different status of copy numbers (predicted to be from gain, loss, or both events) (Table 1).
These 18 CNVRs represent different predicted status of copy numbers (i.e., loss, gain and both) and different CNVR frequencies (varied from 0.84 to 18.57%).
These CNVRs represent different status of copy number variation (i.e., loss, gain and both) and different CNVR frequencies (varied from 1.17 to 98.86%) (Additional file 1: Table S3).
From the total 758 CNVRs identified in the study, 19 CNVRs, representing different predicted status of copy numbers (i.e., loss, gain, and both) and different CNVR frequencies (varying from 8.33 to 100%), were chosen to be validated by qPCR.
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The function of monuments as lieux de mémoire for travelers and intellectuals like Pausanias and Plutarch, the status of copies in Roman imperial culture, the manifestation of artistic identity through artists' signatures and in ancient discourses on art, are among the themes he has been addressing in this context.
Typically, GCN changes observed from a-CGH experiments are classified into three groups corresponding to the three statuses of copy number changes amplification, deletion and normal; Thus, allowing the microarray responses to have similar features.
Law Library holdings display in individual Title pages, showing the current location, call number, and status of each copy.
Then, using information available through computer networks, he examined the status of every copy of those books in 19 British and 13 American academic library systems.
If the LP moved without notification, the status of the copy is updated as parked at the Home SP and managed as specified in the following section.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com